Package: revert
Type: Package
Title: Reversion Mutation Detector for DNA Sequencing Data
Version: 1.0.0
Date: 2025-12-16
Authors@R: c(
	person("Hui", "Xiao", role = c("aut", "cre"), email = "hui.xiao@icr.ac.uk"),
	person("Stephen", "Pettitt", role = "aut", email = "stephen.pettitt@icr.ac.uk"),
	person("Syed", "Haider", role = c("aut"), email = "Syed.Haider@icr.ac.uk")
  )
Author: Hui Xiao [aut, cre],
  Stephen Pettitt [aut],
  Syed Haider [aut]
Maintainer: Hui Xiao <hui.xiao@icr.ac.uk>
Description: Reversion mutations are secondary mutations that reverse the deleterious effects of an original pathogenic mutation, partially or fully restoring the gene's function. The revert package detects reversion mutations for a specific pathogenic mutation from DNA-seq bam files. 
Depends: R (>= 4.4.0)
License: GPL-2
Imports: BSgenome, BiocGenerics, Biostrings, GenomeInfoDb,
        GenomicRanges, IRanges, Rsamtools, S4Vectors, ensembldb,
        pwalign, stats, utils
Suggests: knitr, rmarkdown, futile.logger, BSgenome.Hsapiens.UCSC.hg19,
        EnsDb.Hsapiens.v75, BSgenome.Hsapiens.UCSC.hg38,
        EnsDb.Hsapiens.v86
RoxygenNote: 7.3.2
Encoding: UTF-8
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2025-12-16 16:31:45 UTC; hxiao
Repository: CRAN
Date/Publication: 2025-12-17 23:30:02 UTC
Built: R 4.5.3; ; 2026-08-10 01:16:45 UTC; windows
